Low-dose persistent organic pollutants and mitochondrial dysfunction in humans
نویسندگان
چکیده
منابع مشابه
Persistent Organic Pollutants ("POPs")
Strictly speaking, all toxins entering the environment can be regarded as environmental poisons. Certain pollutants can, acting over long periods, harm living organisms even in low concentrations. This means that pollutants that are stable and thus persistent have a great ability to act as environmental poisons. Their stability means not only that their effects are long-lasting, but also that t...
متن کاملSerum Persistent Organic Pollutants
Persistent organic pollutants (POPs) are manmade organic chemicals that remain in the environment for years or decades. POPs are of special concern because they often remain toxic for decades or longer after release to the environment. The more persistent a toxic chemical is, the greater the probability for human exposure over time. Because they circulate globally long after being released into...
متن کاملAssociation of Low-Dose Exposure to Persistent Organic Pollutants with Global DNA Hypomethylation in Healthy Koreans
BACKGROUND Global DNA methylation levels have been reported to be inversely associated with blood levels of persistent organic pollutants (POPs), xenobiotics that accumulate in adipose tissue. Whether these associations extend to a population with much lower concentrations of POPs is not known. OBJECTIVES This study was performed to examine whether low-dose exposure to POPs was associated wit...
متن کاملLow-dose persistent organic pollutants increased telomere length in peripheral leukocytes of healthy Koreans.
Although shortened telomeres have been found in many cancers, elongated telomere length has been observed as an early response after low-dose treatment with various chemical carcinogens in vitro and animal experiments, suggesting low-dose exposure to carcinogenic chemicals may function as a tumour promoter at the very early stage of carcinogenesis in humans. This cross-sectional study was perfo...
متن کاملLow Dose of Some Persistent Organic Pollutants Predicts Type 2 Diabetes: A Nested Case–Control Study
BACKGROUND Low doses of some persistent organic pollutants (POPs) associate cross-sectionally with type 2 diabetes, whereas associations with high POP exposures are inconsistent. OBJECTIVES We investigated whether several POPs prospectively predict type 2 diabetes within the Coronary Artery Risk Development in Young Adults (CARDIA) cohort. METHODS Participants in this nested case-control st...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Environmental Epidemiology
سال: 2019
ISSN: 2474-7882
DOI: 10.1097/01.ee9.0000608360.02525.4a